Crater lake would be quite a trek for a day visit.
Is this your first time in the area?
What is your tolerance for tourist trap type towns? If low, I'd avoid Seaside/Cannon Beach. Particularly in April, though a pleasant day long drive could be Portland to Lincoln City then north to Astoria and back to Portland and just stop wheverever the mood and scenery strike.
If you like zoos, the Washington Park Zoo or Oregon Zoo (whatever it is called these days) is, in my opinion, one of the best zoos in the country. Powell's is one of the best bookstores in the country though I hardly ever stop by anymore (massive selection no longer has quite the appeal to me now that the internet provides infinitely more massive selection).
If you're into such things, a drive up the gorge to Vista House, Multnomah Falls, and if you're brave enough in April, Onteonta Gorge are all very pleasant days (though make sure you take the scenic road rather than just shooting straight out on I-84.
From this list you can see I'm not much of a "city tourist" and find Portland to be lacking in that regard anyway (but that could just be familiarity) and haven't much to recomment. The museums are mostly standard (including OMSI which is extensive but essentially identical to a dozen other MSIs around the country). However, if such are your thing, the core of Portland is actually very small so you can just stroll around and see most of it. But ultimately my recommendation would be to ignore Portland and go see things within a day's drive of it.
I've been to Corvallis many times (particularly when I was young since the JW district conference center is in Corvallis) but honestly can't remember a thing about the area (other than the district conference center).
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