My friend owns a bio-cleanup service, and their equipment is pretty heavy-duty. It completely eradicates a place of dead body odor and the like, so I imagine there is similar equipment for smoke removal.
I no longer smoke, but I will never agree with discriminating against smokers. If a business decides to not allow it (I mean, how hard is it to set aside a few rooms out of the thousands they have?) then that's their right, but they're telling a good chunk of their market they don't want them around.
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