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The book is really pretty straightforward and isn't so much about the events as the ending and what it means. Frankly, I don't know how the book could really be translated to film without drastic changes (and, in fact, the first two times it has been movie-ized it was been change very drastically).
It was previously turned into The Last Man on Earth with Vincent Price and The Omega Man with Charlton Heston. This one looks like it may be more faithful but there are quite a few things in the trailer that are definitely different from the book (moved from LA to New York, for example).
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