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The Oxford or serial comma is completely a choice of style (though using it is more commonly American while not is more commonly British). I prefer to have it (simply because to me the ambiguity caused by absence is more annoying than the ambiguity caused by its presence).
But if I'm a descriptivist when it comes to usage of language I am outright indifferent when it comes to punctuation rules (we need them and should generally follow the agreed upon rules but they are fundamentally arbitrary and do not have any inherent rightness).
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