Zotob.A is a worm targeting Windows 2000–based systems which takes advantage of a security issue that was addressed by Microsoft Security Bulletin MS05-039. This worm installs malicious software, and then looks for other computers to infect.
Important If you have installed the update released with Security Bulletin MS05-039, you are already protected from Zotob.A. If you are using any supported version of Windows 
other than Windows 2000, you are not at risk from Zotob.A.
As part of our Software Security Incident Response Process, our investigation has determined that only a small number of customers have been affected, and Microsoft security professionals are working directly with them. We have seen no indication of widespread impact to the Internet. Customers who believe they have been attacked should contact their local FBI office or post their complaint on the 
Internet Fraud Complaint Center Web site. Customers outside of the United States should contact the national law enforcement agency in their country.
 
Check for Infection
When Zotob.A infects a computer, it attempts to deliver a malicious file named Botzor.exe. If your computer is infected, this file will be present and your registry will show changes. Use any of the following methods to check for infection. (If you find the file, you do not need to check the registry, and vice versa.)
Search your computer for the Botzor.exe file
1.
Click 
Start, point to 
Search, and then click 
For Files and Folders.
2.
Click 
Use Advanced Search Options. Under 
Search by any or all of the criteria below, enter the following information:
A. Under 
All or part of the file name: enter 
Botzor.exe.
B. Under 
Look in: click 
Local Hard Drives.
C. Under 
More Advanced Options, select 
Search system folders and 
Search hidden files and folders.
3.
Click 
Search.
Look for new keys added to the registry
•In registry key 
HKLM\Software\Microsoft\Windows\
CurrentVersion\Run added value 
WINDOWS SYSTEM with data of 
botzor.exe
•In registry key 
HKLM\Software\Microsoft\Windows\
CurrentVersion\RunServices added value 
WINDOWS SYSTEM with data 
botzor.exe
If Your Computer Is Not Infected
Help protect your computer against Zotob.A by installing Security Update 899588. Find the download link for your version of Windows in 
Microsoft Security Bulletin MS05-039.
If Your Computer Is Infected
Follow the Zotob.A 
recovery steps in the Microsoft Antivirus Encyclopedia.