Yes, it's possible. But GD was, I believe, speaking as a hypothetical voter on the confirmation of Roberts. If such a Senator Delight was of the opinion that the candidate for confirmation was reading the Constitution all wrong, it would be incumbant upon Senator Delight to vote "NO" based on the candidate being unqualified to do the job.
It goes without saying that Senator Delight MUST hold his own opinions on reading the Constitution to be the correct opinions, for one cannot have opinions which one considers wrong. The objective possibility may be that Delight is wrong and Roberts is right, but it's impossible for Senator Delight to have that view, and thus his vote must be "Nay."
Edited to add: I wasn't quick enough to say longwindedly what GD said quite sucinctly. But I like mine better, cause I love the concept of "Senator Delight."
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