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Regulating my breathing is all I need to get over an oncoming panick attack. By just paying attention to it, you tend to breath more deeply, more slowly ... this slows the heart rate, calms the nerves.
For more persistent anxiety .... I simply suffer it. No cure known to me.
BTW, if you're upcoming vacation is going to be your general life anxiety-reliever, I don't see how you could give it up. Postponement might be a neet idea though. (and if it's really going "back east," um, yeah, giving it up might be all the stress relief you need.)
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